Venous oxygen saturation estimation from multiple T2 maps with varying inter-echo spacing
نویسندگان
چکیده
Background Dependence of blood T2 on O2 saturation has led to noninvasive MRI-based techniques for determining venous O2 saturation (SvO2) [1-3]. However, applying a general calibration factor derived from in vitro experiments can lead to inaccurate and largely varying SvO2 estimates in the target population. We aim to show that based on the Luz-Meiboom relation 1/T2 = 1/T2o + Hct(1-Hct) τex [(1-%SO2/100)aω0] (1-2*τex/τ180 tanh(τ180/2*τex))[4], individual SvO2 can be determined from multiple T2 maps, each acquired at a specific inter-echo spacing (τ180).
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