Information Modeling for Pharmaceutical Product Development
نویسندگان
چکیده
Development of a pharmaceutical product involves several inter-related steps with multiple decisions requiring iterative improvements. Large amounts of information, including the properties of a drug substance, interactions of materials, unit operations, equipment etc, have to be gathered and used for decision making. A systematic model of the associated information is thus needed to streamline the product development process and provide a common foundation to support the information. Following the information-centric infrastructure proposed in our earlier work, ontology has been used to model the information. The information modeled as ontology provides information in a way that can be easily used by humans and processed by machines. The information modeling process and developed ontology are discussed in detail. The benefits are demonstrated by using a case study for managing information generated from the preformulation stage of pharmaceutical product development.
منابع مشابه
New Product Development in the Pharmaceutical Industry: Evidence from Iran
In today’s competitive world, there are several strategies to deal with the fast changing environment, among which New product development (NPD) is a common strategy. However, almost half of the resources that companies devote to NPD are spent on products that may fail. This issue is particularly highlighted in the pharmaceutical industry mainly because of a long development-time, low success r...
متن کاملNew Product Development in the Pharmaceutical Industry: Evidence from Iran
In today’s competitive world, there are several strategies to deal with the fast changing environment, among which New product development (NPD) is a common strategy. However, almost half of the resources that companies devote to NPD are spent on products that may fail. This issue is particularly highlighted in the pharmaceutical industry mainly because of a long development-time, low success r...
متن کاملAn Ontology-Based Information Management System for Pharmaceutical Product Development
The development of pharmaceutical products and processes involves laboratory scale, pilot plant scale and commercial scale manufacturing. Through these steps, data on synthesis routes, material properties, processing steps, and scale up parameters are collected and used. Recent advances in process analytical technologies resulted in a large volume of heterogeneous data, which requires a systema...
متن کاملA Unified Approach for Knowledge Modeling in Pharmaceutical Product Development
Development of a drug product is a complex, iterative process consisting of selection of a dosage form, excipients, processing route, operating equipment and so on. At each stage, knowledge in various forms, including heuristics, decision trees and mathematical models, is used in making decisions. Typically knowledge is modeled specifically for the tool that uses it, such as expert systems and ...
متن کاملEffects of the Use of ICT on Pharmaceutical Product Marketing in Nigeria
This paper discussed the application of Information and Communication Technology (ICT) in pharmaceutical product marketing in Nigeria. Data for the study was obtained from 76 pharmaceutical firms in southwest Nigeria which comprised of about 95% of the pharmaceutical companies that were into manufacturing of drugs in Nigeria. The categories of firms surveyed include retail pharmacy, combination...
متن کامل