p-Methoxybenzyl ether cleavage by polymer-supported sulfonamides.
نویسندگان
چکیده
[reaction: see text] p-Methoxybenzyl ethers have been found to transfer from alcohols to sulfonamides in the presence of catalytic trifluoromethanesulfonic acid. This process for protecting group removal can be performed in solution with yields >94%. Through the use of sulfonamide-functionalized ("safety-catch") resins, p-methoxybenzyl ethers can be cleaved in excellent yields with minimal purification.
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ورودعنوان ژورنال:
- Organic letters
دوره 4 7 شماره
صفحات -
تاریخ انتشار 2002