A General Scheme for Automatically Building 3D Morphometric Anatomical Atlases: application to a Skull Atlas

نویسندگان

  • Gérard Subsol
  • Jean-Philippe Thirion
  • Nicholas Ayache
چکیده

In this research report, we present a general scheme for building entirely automatically a morphometric anatomical atlas from 3D medical images (CT-Scan, Magnetic Resonance Imagery). We detail each step of the method, including the non-rigid registration algorithm, 3D feature lines averaging, and statistical processes. We apply the method to obtain a quantitative atlas of crest lines of the skull. Finally, we use the resulting atlas to study a craniofacial disease: we show how we can obtain qualitative and quantitative medical results by contrasting a skull aaected by Crouzon's disease with the atlas. Une mmthode ggnnrale pour construire automatiquement des atlas anatomiques morphomtriques : application a un atlas du crrne RRsumm : Dans ce rapport, nous prrsentons une mmthode ggnnrale pour construire de maniire automatique des atlas anatomiques morphommtriques partir d'images mmdicales tridimensionnelles (obtenues par scannographie ou Imagerie par RRsonance Magnntique). Nous ddtaillons les tapes de la mm-thode, en particulier, les algorithmes de mise en correspondance non-rigide, de moyenne de lignes caracttristiques tridimensionnelles et d'analyse statistique. Nous appliquons la mmthode la construction d'un atlas quantitatif des lignes de crrte du crrne. Nous utilisons alors l'atlas pour tudier des diior-mitts craniofaciales ; nous montrons comment la comparaison entre l'atlas et un crrne ddformm par la maladie de Crouzon permet d'obtenir des rrsultats qualitatifs et quantitatifs utilisables par un mmdecin.

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A scheme for automatically building three-dimensional morphometric anatomical atlases: application to a skull atlas

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تاریخ انتشار 1995