A case of mucous membrane pemphigoid involving the trachea and bronchus with autoantibodies to β3 subunit of laminin-332.
نویسندگان
چکیده
منابع مشابه
Prevalence and clinical significance of anti-laminin 332 autoantibodies detected by a novel enzyme-linked immunosorbent assay in mucous membrane pemphigoid.
IMPORTANCE A rare variant of mucous membrane pemphigoid (MMP) is characterized by circulating anti-laminin 332 (Lam332) autoantibodies and seems to be associated with concurrent malignant neoplasms. OBJECTIVE To determine the prevalence and clinical significance of anti-Lam332 autoantibody detection from a large series of patients with MMP. DESIGN Multicenter retrospective study. SETTING ...
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34-year-old African American female with history of pemphigoid presented with hemoptysis. Patient was found to have mucous membrane pemphigoid involving the oropharynx and extending to trachea, till just above main stem carina. Four other cases described mucosal pemphigoid involving the trachea. We hereby present a brief review of current consensus on management of mucous membrane pemphigoid wi...
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PURPOSE To report an anti-epiligrin cicatricial pemphigoid (AECP) patient with severe ocular involvement and to provide a practical approach to distinguishing AECP patients from those with other subepidermal blistering diseases. METHODS Techniques included direct and indirect immunofluorescence microscopy, Western blot and immunoprecipitation studies, as well as interdisciplinary examinations...
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متن کاملA case of linear IgA/IgG bullous dermatosis with anti-laminin-332 autoantibodies.
Fig. S1. Immunoblot analysis using purified human laminin-332. Lane 1 is for IgG autoantibodies of anti-laminin-332 MMP control, lane 2 for IgG autoantibodies of normal control, lane 3 for patient IgG autoantibodies, and lane 4 for patient IgA autoantibodies. Both IgG and IgA from the patient reacted with the 165-kDa and 145-kDa forms of α3 subunit, as well as the 105-kDa γ2 subunit of laminin-...
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عنوان ژورنال:
- Acta dermato-venereologica
دوره 94 2 شماره
صفحات -
تاریخ انتشار 2014