Sapwood of Carob Tree (Ceratonia siliqua L.) as a Potential Source of Bioactive Compounds

Phytochemical Investigation, Antioxidant Properties, and Identification of Organic and Inorganic Compounds from the Carob (Ceratonia siliqua L.) Fruit

Introduction: Carob (Ceratonia siliqua L.) is a tree belonging to the Leguminosae family. It is used for forestry and ornamental purposes. The tree is of importance due to its medicinal properties and its ability to treat infertility.  The present study aimed to investigate the chemical composition and fatty acid profile of the fruit.   Materials & Methods: Maximum extraction yields of the fr...

Effects of salinity and drought stress on growth and echophysiolgical parameters in carob tree seedlings (Ceratonia siliqua L.)

Evaluation of Carob (Ceratonia siliqua) and Honey Locust (Gleditsia triacanthos) Pods as a Feed for Sheep

The nutritive value of Ceratonia siliqua and Gleditsia triacanthos pods was determined on the basis of their chemical composition, in vitro gas production and rumen fermentation end-products. Medicago sativa was used as a reference feed material. The studied samples showed differences in chemical composition and phenolic compounds. Crude protein (CP) content was particulary low (80 g/kg DM) in ...

Antiproliferative effects of Ceratonia siliqua L. on mouse hepatocellular carcinoma cell line.

Extracts from pods and leaves of carob (Ceratonia siliqua L.) were tested for their ability to inhibit cell proliferation of mouse hepatocellular carcinoma cell line (T1). The two extracts showed a marked alteration of T1 cell proliferation in a dose-related fashion reaching the maximal effect at 1 mg/ml. Moreover, we demonstrated that leaf and pod extracts were able to induce apoptosis in T1 c...

Carob (Ceratonia siliqua L.) fruit hydro-alcoholic extract alleviates reproductive toxicity of lead in male mice: Evidence on sperm parameters, sex hormones, oxidative stress biomarkers and expression of Nrf2 and iNOS

Objective: Carob (Ceratonia siliqua L.) is an evergreen tree with fruits that have potent antioxidant activity. The aim of this study was to investigate alleviative effects of carob fruit hydro-alcoholic extract (CFHAE) against reproductive toxicity induced by lead (Pb) in male mice. Material and Methods: Forty-two NMRI adult male mice were randomly categorized into 7 groups (N=6). Group ...