Dexmedetomidine as adjuvant for peripheral nerve blocks.
نویسنده
چکیده
Marhofer and colleagues Malenfant Rancourt and colleagues Site Ulnar nerve (volunteers) Posterior tibial nerve (volunteers) Medication 3 ml ropivacaine 0.75% 10 ml ropivacaine 0.5% Dose of adjuvant 20 mg dexmedetomidine 1 mg kg dexmedetomidine ( 50–70 mg) Results Sensory block 350(SD 54) min ropivacaine only(5.8 h) vs 555 (118) min ropivacaine+ dexmedetomidine (9.25 h) 972 (SD 120) min ropivacaine only (16.2 h) vs 1290 (SD 72) min ropivacaine+ dexmedetomidine (21.5 h) Side-effects No haemodynamic variations Noticeable decrease in blood pressure and lowered heart rate in certain volunteers Complications None None
منابع مشابه
Facilitatory effects of perineural dexmedetomidine on neuraxial and peripheral nerve block: a systematic review and meta-analysis.
UNLABELLED Nerve blocks improve postoperative analgesia, but their benefits may be short-lived. This quantitative review examines whether perineural dexmedetomidine as a local anaesthetic (LA) adjuvant for neuraxial and peripheral nerve blocks can prolong the duration of analgesia compared with LA alone. All randomized controlled trials (RCTs) comparing the effect of dexmedetomidine as an LA ad...
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Objectives: Dexmedetomidine has been utilized as an adjuvant to prolong single local anaesthetic injection technique in brachial plexus block despite of adverse effects and cost-effectiveness. Morphine, a classic opioid, is also used as an adjuvant in neuraxial and perineural nerve blocks. In this study, we compared the effects of these two different adjuvants to ropivacaine in interscalene bra...
متن کاملLocal Anesthetic Peripheral Nerve Block Adjuvants for Prolongation of Analgesia: A Systematic Qualitative Review
BACKGROUND The use of peripheral nerve blocks for anesthesia and postoperative analgesia has increased significantly in recent years. Adjuvants are frequently added to local anesthetics to prolong analgesia following peripheral nerve blockade. Numerous randomized controlled trials and meta-analyses have examined the pros and cons of the use of various individual adjuvants. OBJECTIVES To syste...
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Background: Alpha-2 agonists are added to local anesthetic agents to extend the duration of peripheral nerve blocks. Objective: We evaluated the effect of combining dexmedetomidine with levobupivacine with respect to duration of motor and sensory block and duration of analgesia. Material and Methods: Sixty patients of ASA grade I or II aged between 18-60 years, posted for elective upper limb su...
متن کاملPerineural Dexmedetomidine as an Adjuvant Reduces the Median Effective Concentration of Lidocaine for Obturator Nerve Blocking: A Double-Blinded Randomized Controlled Trial
UNLABELLED Research suggests that the addition of dexmedetomidine to local anesthetics can prolong peripheral nerve blocks; however, it is not known whether dexmedetomidine can reduce the quantity of local anesthetic needed. We hypothesized that adding dexmedetomidine as an adjuvant to an obturator nerve block could reduce the median effective concentration of lidocaine. In this double-blinded ...
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ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 111 1 شماره
صفحات -
تاریخ انتشار 2013