Gluten-free diet in the management of patients with irritable bowel syndrome, fibromyalgia and lymphocytic enteritis
نویسنده
چکیده
An evaluation of the effect of 1 year of a gluten-free diet was performed in patients with irritable bowel syndrome and fibromyalgia syndrome displaying lymphocytic enteritis. Gluten withdrawal produced a slight but significant improvement of the functional symptoms, suggesting that gluten might be partly responsible for this clinical picture. This hypothesis should be confirmed by a double-blind placebo-controlled trial since it cannot be ruled out that the studied patients displayed a subjective sensation of improvement due to the placebo effect of gluten withdrawal. Further investigations are needed before recommending gluten withdrawal in patients with fibromyalgia and lymphocytic enteritis.
منابع مشابه
Effect of one year of a gluten-free diet on the clinical evolution of irritable bowel syndrome plus fibromyalgia in patients with associated lymphocytic enteritis: a case-control study
INTRODUCTION Irritable bowel syndrome (IBS), lymphocytic enteritis (LE) and fibromyalgia syndrome (FMS) are three common disorders. Since a gluten-free diet (GFD) has been shown to be helpful in LE, we aimed to assess its effect in a series of LE patients also diagnosed with IBS and FMS. METHODS The study sample comprised 97 IBS plus FMS adult females, of whom 58 had LE (Marsh stage 1), and 3...
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Background & Aims: Celiac disease or gluten-sensitive enteropathy is a relatively uncommon digestive disease. Moreover, irritable bowel syndrome (IBS) is a common functional bowel disorder. Some IBS patients have celiac disease, with similar IBS symptoms in addition to some serious complications. The only possible treatment for this condition is changing the patients diet (gluten free diet). Gi...
متن کاملResponse to ‘Remarkable prevalence of celiac disease in patients with irritable bowel syndrome plus fibromyalgia in comparison with those with isolated irritable bowel syndrome: a case-finding study’
In a recent issue of Arthritis Research & Therapy, I read with interest the report by Rodrigo and colleagues [1] documenting a fairly high rate of celiac disease in patients with irritable bowel syndrome and fibromyalgia. It is noteworthy that their patients improved on a gluten-free diet. However, that article references the report by Taubman and colleagues [2] and implies that our patient imp...
متن کاملResponse to ‘Remarkable prevalence of celiac disease in patients with irritable bowel syndrome plus fibromyalgia in comparison with those with isolated irritable bowel syndrome: a case-finding study’ – authors’ reply
We greatly appreciate Sherry’s comments [1] on our recent article published in Arthritis Research & Therapy [2], and we agree with him that, although the majority of patients with celiac disease (CD) and fibromyalgia syndrome (FMS) may improve with a gluten-free diet (GFD), this may not be a uniform phenomenon. However, we believe that his observations in children [3] cannot be extrapolated to ...
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Microscopic enteritis (ME) is characterized by abnormal infiltration of intraepithelial lymphocytes in intestinal mucosa. It was described as duodenal lymphocytosis or lymphocytic duodenitis until the dedicated Consensus Conference of 2015. ME represents a common feature of several gluten-mediated and non-gluten related diseases; therefore, it is an umbrella term embracing several conditions. T...
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