Perfect simulation from nonneutral population genetic models: variable population size and population subdivision.
نویسنده
چکیده
We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models. We specifically consider a biallelic locus and either a general variable population size mode or a general migration model for population subdivision. We investigate the effect of demography on the efficacy of selection and the effect of selection on genetic divergence between populations.
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ورودعنوان ژورنال:
- Genetics
دوره 174 3 شماره
صفحات -
تاریخ انتشار 2006