Diagnosis, Treatment and Prevention of Pregnancy Toxemia in Ewes

Thin ewes or very over-conditioned ewes and ewes carrying multiple pregnancies are more likely to develop pregnancy toxemia (ketosis). Pregnancy toxemia is a metabolic disorder characterized by hypoglycemia and hyperketonemia resulting from incapacity of the ewes to maintain adequate energy balance (usually in the last 5-6 weeks). Available information about pregnancy toxemia focuses mainly on pathogenic mechanisms and clinical features, early diagnosis, and therapeutic options. However, the pathophysiology and metabolic changes of this disorder remain poorly understood. An immediate and accurate diagnosis usually increases the possibility for their successive treatment and prevention. The objective of this review was to increase awareness of the disease, its likely cause, and practical treatment and prevention measures.