The action of British anti-lewisite (BAL) on enzyme systems.

نویسندگان

  • E C Webb
  • R Van Heyningen
چکیده

Barron, E. S. G. & Singer, T. P. (1945). J. biol. Chem. 157, 221. Cohen, A., King, H. & Strangeways, W. I. (1931). J. chem. Soc. p. 3043. Eagle, H. (1939). J. Pharmacol. 66, 436. Hopkins, F. G. & Morgan, E. J. (1938). Biochem. J. 32,611. Peters, R. A., Sinclair, H. M. & Thompson, R. H. S. (1940). Report to Ministry of Supply, no. 4.* Peters, R. A., Sinclair, H. M. & Thompson, R. H. S. (1946). Biochem. J. 40, 516. Peters, R. A., Stocken, L. A. & Thompson, R. H. S. (1945). Nature, Lond., 156, 616. Singer, T. P. & Barron, E. S. G. (1945). J. biol. Chem. 157, 241. Stocken, L. A. & Thompson, R. H. S. (1940, 1941). Report to Ministry of Supply by Peters, nos. 20, 29 and 33.* Voegtlin, C., Dyer, H. & Leonard, C. S. (1923). U.S. Pub. Hlth Rep. 38, 1882. Voegtlin, C., Rosenthal, S. M. & Johnson, J. M. (1931). U.S. Pub. Hlth Rep. 40, 339.

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The development of 2,3-dimercaptopropanol (British Anti-Lewisite, BAL) by Peters, Stocken, and Thompson (1) has made available a potent antidote for arsenical poisoning. Study of the chemical combination of arsenic with sensitive enzymes and cells indicated that the arsenic could, under certain circumstances, be removed from the cells, and that enzymes could be reactivated by the action of BAL ...

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عنوان ژورنال:
  • The Biochemical journal

دوره 41 1  شماره 

صفحات  -

تاریخ انتشار 1947