Response by Caplan et al.

Angiogenesis and the Pathogenesis of Autosomal Dominant Polycystic Kidney Disease

Occurring with an incidence between 1/400 – 1/1000 live births autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disorder affecting the kidney (Ecder et al., 2007). The disease results from mutation in either of two genes PKD1, located on chromosome 16p13.3 or PKD2, located on chromosome 4q21 and is inherited in an autosomal dominant manner (Euro...

Public Participation: Methods Matter; A Response to Boaz et al.

Prediction of Patient’s Response to Cognitive-Behavior Therapy by Artificial Neural Network

Objective: Social anxiety disorder (SAD) is defined as a constant fear of being embarrassed or negatively evaluated in social situations or while doing activities in the presence of others. Several studies have examined the role of certain variables that might predict response to treatment and may affect treatment outcome. The purpose of this study was to identify predictive variables of change...

Molecular Imaging of the Paracrine Proangiogenic Effects of Progenitor Cell Therapy in Limb Ischemia Running title: Ryu et al.; Molecular Imaging of Stem Cell Paracrine Effects

Evaluation of the performance of the CMIP5 General Circulation Models in predicting the Indian Ocean Monsoon precipitation over south Sistan and Baluchestan, using the past hydrological changes in the region

1-Introduction Climate change refers to any significant change in the existing mean climatic conditions within a certain time period (Jana and Majumder, 2010; Giorgi, 2006). Earth's climate change through history has happened (Nakicenovic et al., 2000; Bytnerowicz et al., 2007). 2-Materials and methods In this study, daily precipitation and daily maximum (Tmax) and daily minimum (Tmin) tempera...

The Use of a Hydrogel Matrix as a Cellular Delivery Vehicle in Future Cell-Based Therapies: Biological and Non-Biological Considerations

Cell therapy is defined as the minimally-invasive delivery of therapeutic cells into a human host to repair damaged or diseased tissue(s). Its long-term goal is to reduce the current expense of 1% of US GDP on organ replacement therapies (Lysaght, et al., 2008). Hematopoietic stem cell transplants are the most popular cell therapy and have been crucial in treating a variety of hematological dis...