A Histopathological Study of Salivary Gland Tumors- a Clinicopathological Study

Background: Salivary gland tumors are relatively uncommon. It accounts for < 2% of all human neoplasms. They pose considerable clinical management challenges because of their confounding histological and behavioral diversity as well as their proximity to important head and neck structures. The present study was conducted to account different salivary gland tumors among different population. Materials & Methods: This is a retrospective study conducted in the department of General Pathology in 5 years duration from 2010-2015. We included all the biopsies visited the department during this period. All biopsy specimens were fixed in 10% formol saline, then processed into paraffinembedded sections and stained with hematoxylin and eosin. Specials stains were occasionally employed. All histology slides were reviewed, and classified according to the World Health Organization (WHO) histological typing of tumors. Results: Out of 8050 biopsies obtained, salivary gland tumors accounts for 85 which make prevalence rate of 1.05%. Out of 85 salivary gland tumors, 50 (58.8%) were seen in females and 35 (41.17%) were seen in males. There was predominance of females over males. The difference was significant (P < 0.05). Among benign tumors, pleomorphic adenoma was seen in males (10) and females (18), oxyphil adenoma in males (5) and females (9), basal cell adenoma in males (2) and females (7), hemangioma in males (3) and females (4) and myoepithelioma in males (2) and females (5). The difference was significant (P < 0.05). Malignant salivary gland tumors, most commonly seen was mucoepidermoid carcinoma in males (3) and females (2), followed by small cell carcinoma in males (2) and females (1), acinic cell carcinoma in males (2) and females (1), basal cell carcinoma in males (2) and females (1), polymorphous low grade adenocarcinoma in males (1) and females (1), acinic cell carcinoma in males (1) and females (1), 1 case of lymphoma and papillary adenocarcinoma was seen in male. The difference was nonsignificant (P > 0.05). Conclusion: Salivary gland tumors accounted for 1.05%. There was predominance of females over males in distribution of salivary gland tumors. Benign tumors were more common as compared to malignant tumors.