Capillary Electrophoresis Improving Clinical Measurement of Clozapine
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A simpler and faster capillary electrophoresis method for determination of mianserin enantiomers in human serum.
A stereospecific sample stacking capillary zone electrophoresis method is described for determination of S(+) and R(-) enantiomers of mianserin (1,2,3,4,10,14b-hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine) in human serum. The enantiomers of mianserin were extracted from human serum in one step extraction procedure using the mixture n-heptane:ethyl acetate (80:20, v/v). After separation ...
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Capillary electrophoresis (CE) with indirect UV detection is an interesting analytical method for the analysis of drugs and pharmaceuticals. Good and reproducible capillary quality is needed to develop robust methods and to facilitate method transfer in CE. It is widely accepted that preconditioning procedures are indispensable in capillary electrophoresis in order to achieve reproducibility of...
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متن کاملEffect of Capillary Rinsing Protocol on the Reproducibility of Separation in Capillary Electrophoresis with Indirect UV Detection
Capillary electrophoresis (CE) with indirect UV detection is an interesting analytical method for the analysis of drugs and pharmaceuticals. Good and reproducible capillary quality is needed to develop robust methods and to facilitate method transfer in CE. It is widely accepted that preconditioning procedures are indispensable in capillary electrophoresis in order to achieve reproducibility of...
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BACKGROUND Hemoglobin (Hb) A1c is widely used as the gold standard for blood glucose level monitoring in diabetic patients. Various methods are being used in clinical laboratories for HbA1c measurement. However, the presence of Hb variants may interfere with HbA1c measurement. METHODS The HbA1c assay was performed routinely in a 55-year old woman with type 2 diabetes and hyperlipidemia that w...
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