Antibodies to herpes group viruses in patients with nasopharyngeal and other head and neck cancers.

phoma and NPC (17, 22), and in lymphoid cell lines derived from such tumors (4, 21). The serological association between EBV and NPC, first established by Old et al. (18), has been strengthened by Henle et al. (12) and others (3, 5, 7, 15, 16) through use of the indirect immunoflourescence test. Virtually 100% of NPC patients have detectable antibody to EBV capsid antigen in high titer (> 1:160). There is no apparent difference in NPC, either in frequency of positive titers or height of such titers, between Chinese cases and other racial groups. Recently, Burkitt's lymphoma and nasopharyngeal pa