First report of KPC-2 Carbapenemase-producing Klebsiella pneumoniae in Japan.

نویسندگان

  • Ryoichi Saito
  • Rieko Takahashi
  • Etsuko Sawabe
  • Saho Koyano
  • Yutaka Takahashi
  • Mari Shima
  • Hiroto Ushizawa
  • Toshihide Fujie
  • Naoki Tosaka
  • Yuko Kato
  • Kyoji Moriya
  • Shuji Tohda
  • Naoko Tojo
  • Ryuji Koike
  • Tetsuo Kubota
چکیده

We investigated a novel Japanese isolate of sequence type 11 (ST11), the Klebsiella pneumoniae carbapenemase-2 (KPC-2)-producing K. pneumoniae strain Kp3018, which was previously obtained from a patient treated at a Brazilian hospital. This strain was resistant to various antibiotic classes, including carbapenems, and harbored the gene blaKPC-2, which was present on the transferable plasmid of ca. 190 kb, in addition to the blaCTX-M-15 gene. Furthermore, the ca. 2.3-kb sequences (ISKpn8-blaKPC-2-ISKpn6-like), encompassing blaKPC-2, were found to be similar to those of K. pneumoniae strains from China.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 58 5  شماره 

صفحات  -

تاریخ انتشار 2014