Non-Hodgkin's lymphoma of thyroid.

Goitres associated with autoimmune thyroid disease may undergo malignant changes. Lymphoma should be considered when such goitres enlarge rapidly. Although Non-Hodgkin lymphoma frequently affects extra nodal sites, primary involvement of thyroid gland is very unusual. However, clinically this tumour may easily be confused with anaplastic carcinoma of thyroid. Early diagnosis with biopsy and treatment with chemotherapy supplemented with or without radiotherapy results in an improved prognosis and may be potentially curative. We report 2 cases of this rare disorder in whom early diagnosis and treatment were very encouraging.