CALL FOR PAPERS Physiology and Pharmacology of Temperature Regulation The median preoptic nucleus is involved in the facilitation of heat-escape/ cold-seeking behavior during systemic salt loading in rats

نویسندگان

  • Masahiro Konishi
  • Kazuyuki Kanosue
  • Masumi Kano
  • Akiko Kobayashi
  • Kei Nagashima
چکیده

Masahiro Konishi, Kazuyuki Kanosue, Masumi Kano, Akiko Kobayashi, and Kei Nagashima Department of Physiology, Course of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; Department of Physiology, Faculty of Sports Sciences and Department of Integrative Physiology, Health and Welfare, Faculty of Human Sciences, Waseda University, Tokorozawa, Saitama, Japan; Consolidated Research Institute for Advanced Science and Medical Care, Waseda University, Tokyo, Japan; and Advanced Research Center for Human Sciences, Waseda University; Tokorozawa, Saitama, Japan

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The median preoptic nucleus is involved in the facilitation of heat-escape/cold-seeking behavior during systemic salt loading in rats.

Systemic salt loading has been reported to facilitate operant heat-escape/cold-seeking behavior. In the present study, we hypothesized that the median preoptic nucleus (MnPO) would be involved in this mechanism. Rats were divided into two groups (n = 6 each): one group had the MnPO lesion with ibotenic acid (4.0 mug) and the other was the vehicle control. After subcutaneous injection (10 ml/kg)...

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Brain regions expressing Fos during thermoregulatory behavior in rats.

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Neural Substrate of Cold-Seeking Behavior in Endotoxin Shock

Systemic inflammation is a leading cause of hospital death. Mild systemic inflammation is accompanied by warmth-seeking behavior (and fever), whereas severe inflammation is associated with cold-seeking behavior (and hypothermia). Both behaviors are adaptive. Which brain structures mediate which behavior is unknown. The involvement of hypothalamic structures, namely, the preoptic area (POA), par...

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تاریخ انتشار 2006