Characterization of a riboflavin non-aqueous nanosuspension prepared by bead milling for cutaneous application.

Itraconazole nanosuspension for oral delivery: Formulation, characterization and in vitro comparison with marketed formulation

BACKGROUND AND THE PURPOSE OF THE STUDY Itraconazole is a poorly water soluble drug which results in its insufficient bioavailability. The purpose of the present study was to formulate Itraconazole in a nanosuspension to increase the aqueous solubility and to improve its formulation related parameters, dissolution and hence oral bioavailability. METHODS Itraconazole nanosuspension was prepare...

Amorphous Indomethacin Nanoparticles Prepared By Aqueous Wet Bead Milling And In Situ Measurement Of Their Increased Solubility

Formulation of Ibuprofen Beads by Ionotropic Gelation

Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...

Formulation of Ibuprofen Beads by Ionotropic Gelation

Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...

Cyclosporine A-Nanosuspension: Formulation, Characterization and In Vivo Comparison with a Marketed Formulation

Cyclosporine A-nanosuspensions were prepared using zirconium oxide beads as a milling media, Poloxamer 407 as a stabilizer and distilled water as an aqueous medium using the Pearl Milling technique. The optimized formulation was characterized in terms of particle size distribution, surface morphology, drug-surfactant interaction, drug content, saturation solubility, osmolarity, and stability. T...