Evaluation of Diuretic Activity of Jussiaea Suffruticosa Linn

The diuretic potential of methanolic extract of whole plant of Jussiaea suffruticosa was evaluated in male albino rats. The volume of urine, urinary concentration of sodium, potassium and chloride ions was the tested parameters of the study. Furosemide (100 mg/kg) was used as standard. Methanolic extract was tested in dose levels of 200 and 400 mg/kg. The methanolic extract at 400 mg/kg dose level produced very significant increase in volume of urine, urinary concentration of sodium, potassium and chloride ions (Na, K and Cl). However, 200 mg/Kg has not shown significant increase in all tested parameters. The methanolic extract showed the presence of alkaloids, steroids, flavonoids, tannins, carbohydrates and glycosides that may either individually or collectively possess natriuretic and diuretic activities.