Sex differences in intracellular Ca accumulation following eccentric contractions of rat skeletal muscle in vivo
نویسندگان
چکیده
Takashi Sonobe, Tadakatsu Inagaki, Mizuki Sudo, David C. Poole, and Yutaka Kano Department of Engineering Science, Bioscience and Technology Program, University of Electro-Communications, Chofu, Tokyo, Japan; National Cardiovascular Center Research Institute, Department of Cardiac Physiology, Suita, Osaka, Japan; Departments of Anatomy, Physiology and Kinesiology, Kansas State University, Manhattan, Kansas; and School of Sports and Health Sciences, University of Exeter, United Kingdom
منابع مشابه
Sex differences in intracellular Ca(2+) accumulation following eccentric contractions of rat skeletal muscle in vivo.
It is commonly believed that estrogen and sex influences play significant effects in skeletal muscle damage following eccentric exercise. The mechanistic bases for this sex-specific phenomenon remain to be resolved. The muscle damage has been linked to loss of Ca(2+) homeostasis and resultant intramyocyte Ca(2+) ([Ca(2+)](i)) accumulation; therefore, we tested the hypothesis that the greater ec...
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Background: The typical features of eccentric exercise-induced muscle damage are delayed-onset muscle soreness (DOMS) and prolonged loss of muscle strength. It has been shown that passive warmth is effective in reducing muscle injury. Due to the interaction of different systems in vivo, we used isolated perfused medial gastrocnemius skeletal muscle to study the direct effect of temperature on t...
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Although the accumulation of intracellular calcium ions ([Ca2+]i) is associated with muscle damage, little is known regarding the temporal profile of muscle [Ca2+]i under in vivo conditions, and, specifically, the effects of different contraction types [e.g., isometric (ISO); eccentric (ECC)] on [Ca2+]i remain to be determined. The following hypotheses were tested. 1) For 90 min at rest, an in ...
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The effect of eccentric contraction on force generation and intracellular pH (pH(i)) regulation was investigated in rat soleus muscle. Eccentric muscle damage was induced by stretching muscle bundles by 30% of the optimal length for a series of 10 tetani. After eccentric contractions, there was reduction in force at all stimulation frequencies and a greater reduction in relative force at low-st...
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