Woman with red urine: hydroxocobalamin-induced chromaturia.
نویسندگان
چکیده
A 92-year-old African-American woman suffered from smoke inhalation during ahousefire.Thepatientwas transferred from a cross-town hospital to receive hyperbaric oxygen (HBO) therapy for carbon monoxide intoxication. Before arrival shewas sedated, intubated, and administered hydroxocobalamin (CyanoKit ; King Pharmaceuticals, Bristol, TN) 5 g intravenously for presumed cyanide poisoning. In the Emergency Department (ED) a Foley catheter was placed and, upon inspection, her urine was tinted a deep red color (Figure 1). The patient received promptHBO treatment andwas transferred to the Intensive Care Unit. The extended duration of hydroxocobalamininduced chromaturia can bemeasured by viewing the urine collection bag on day 8 (Figure 2). Despite mechanical ventilation, HBO therapy, and treatment for cyanide toxicity, the patient suffered cardiopulmonary arrestwhile in the Intensive Care Unit and passed away days later.
منابع مشابه
Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation.
This chart review was undertaken to assess efficacy and safety of hydroxocobalamin for acute cyanide poisoning. Hospital records of the Fernand Widal and Lariboisière Hospitals were reviewed for intensive care unit admissions with cyanide poisoning for which hydroxocobalamin was used as first-line treatment from 1988 to 2003. Smoke inhalation cases were excluded. Hydroxocobalamin (5-20 g) was a...
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The radioactive material in urine after parenteral radioactive hydroxocobalamin is composed of radioactive cyanocobalamin, radioactive hydroxocobalamin, and a radioactive anionic complex. Studies in vitro suggest that these materials have a similar microbiological activity. Comparison of the amounts of radioactive and microbiologically active material in urine after parenteral radioactive hydro...
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ESULTS OF STUDIES reported in Part I of this paper gave evidence that hydroxocobalamin is excreted in the urine more slowly and builds up consistently higher and more prolonged vitamin B12 levels in the blood as compared to cyanocobalamin. We therefore made a comparative study of the absorption of labelled hydroxocobalamin and cyanocobalamin from the site of injection and the uptake of each by ...
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ورودعنوان ژورنال:
- The Journal of emergency medicine
دوره 43 3 شماره
صفحات -
تاریخ انتشار 2012