Abstracts from the Third International Damage Associated Molecular Pattern Molecules (DAMPs) and Alarmins Symposium.

نویسندگان

  • Michael T. Lotze
  • Helena Erlandsson Harris
چکیده

Submission Please submit late-breaking abstracts at: https://ccehs.upmc.edu/formalCourses.jsp#1572 Please be sure to select one of the following sessions for your submittal: • DAMPs and Alarmins Receptors RAGE, IL1Rs, TLRs, NLRs, and RLRs • Advances in DAMPs and Alarmins • Clinical and Preclinical Studies of DAMPs and Alarmins Meeting Location The conference will be held at the Herberman Conference Center located within the UPMC Shadyside Cancer Pavilion, 5150 Centre Avenue, Pittsburgh, PA 15232.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

DAMPs, PAMPs and alarmins: all we need to know about danger.

Multicellular animals detect pathogens via a set of receptors that recognize pathogen-associated molecular patterns (PAMPs). However, pathogens are not the only causative agents of tissue and cell damage: trauma is another one. Evidence is accumulating that trauma and its associated tissue damage are recognized at the cell level via receptor-mediated detection of intracellular proteins released...

متن کامل

Cell death in the pathogenesis of immune-mediated diseases: the role of HMGB1 and DAMP-PAMP complexes.

Cell death is a ubiquitous process whose immunological consequences can influence the course of infectious, autoimmune and inflammatory diseases. While cell death has long been dichotomised in terms of apoptosis and necrosis, other forms of death can occur and they vary in their capacity to stimulate as well as inhibit inflammation. The pro-inflammatory activity of dead cells results from a wid...

متن کامل

PReS-FINAL-2340: A pathogenic role for S100A8/A9 in experimental autoimmune arthritis

Introduction Damage Associated Molecular Pattern molecules (DAMPs) like HMGB1 have been demonstrated to be involved in pathological processes triggering and perpetuating autoimmune arthritis by attraction and activation of immune cells. The phagocyte-specific S100 proteins A8 and A9 (Myeloid Related Protein 8 and 14, respectively) are expressed by monoyctes and granulocytes and can likewise ope...

متن کامل

Toll-like receptor--a potent driving force behind rheumatoid arthritis.

Toll like receptor (TLR), one of the key functions of innate immune system, can recognize not only exogenous pathogen-associated molecular patterns, namely PAMPs, but also endogenous molecules created upon tissue injury, sterile inflammation and degeneration. Endogenous TLR ligands are called as damage-associated molecular patters (DAMPs), including endogenous molecules released by activated an...

متن کامل

Rage mediated DAMP signaling in intestinal tumorigenesis

In the intestine, a large variety of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) can instigate innate immune responses, which have been shown to promote colorectal carcinogenesis. We have recently demonstrated an important role for the receptor for advanced glycation end products (Rage) in intestinal adenoma formation. Rage is a receptor for D...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of leukocyte biology

دوره 84 2  شماره 

صفحات  -

تاریخ انتشار 2008