Receptors on Immunocompetent Cells

Differences of IL-1β Receptors Expression by Immunocompetent Cells Subsets in Rheumatoid Arthritis

IL-1β is involved in the induction and maintenance of chronic inflammation in rheumatoid arthritis (RA). Its activity is regulated and induced by soluble and membrane-bound receptors, respectively. The effectiveness of the cytokine depends not only on the percentage of receptor-positive cells in an immunocompetent subset but also on the density of receptor expression. The objective of this stud...

SHARED IDIOTYPIC DETERMINANTS ON B AND T LYMPHOCYTES REACTIVE AGAINST THE SAME ANTIGENIC DETERMINANTS I . Demonstration of Similar or Identical Idiotypes on IgG Molecules and T-Cell Receptors with Specificity for the Same Alloantigens*

The immunocompetent cells that can recognize foreign structures by their own actively synthesized antigen-binding receptors are the lymphocytes (1). Two major groups of lymphocytes exist, with separate functions andwithout ability to transform into each other (2, 3) . One group is called T lymphocytes, due to their dependence on the presence of the thymus for development (2). The second group o...

Adiponectin Effect on The Viability of Human Endometrial Stromal Cells and mRNA Expression of Adiponectin Receptors

Cellular Receptors

The possibility that a rat alloantiserum DA anti-Lewis possesses similar recognition structures for Lewis transplantation antigens, as do DA immunocompetent cells, was investigated by raising an antiserum against this alloantiserum in (Lewis x DA)F(1) hosts. This antiserum, as well as one provoked by injecting DA lymphoid cells, was active against recognition structures for Lewis antigens of DA...

Molecular mechanisms regulating B-cell negative selection.

The commitment of a pluripotential stem cell to the B-cell lineage and the progression of the committed B-cell precursor to a mature, immunocompetent B-cell is a highly regulated process. Extrinsic processes and internal programmes initiate and regulate the changes in gene expression that alter the phenotype and functional characteristics of the B-cell as it proceeds through its maturation. Man...

Biological behaviors of muscarinic receptors in mesenchymal stem cells derived from human placenta and bone marrow

Objective(s): Cells perform their functional activities by communicating with each other through endogenous substances and receptors. Post-translation, stem cells function properly in new host tissue by carrying specific cell surface receptors. We aimed to characterize muscarinic receptor subtypes in mesenchymal stem cells (MSCs) together with osteogenic and adipogenic...