Proliferative activity in bilateral paraneoplastic melanocytic proliferation and bilateral uveal melanoma.

Bilateral diffuse uveal melanocytic hyperplasia (BDUMH) is a rare but well known paraneoplastic syndrome,' associated with systemic malignancy. An essential feature of this syndrome is a preponderantly benign looking cytology of the melanocytic tumours.' We describe the clinical and histopathological features ofBDUMH with active proliferation and bilateral ciliary body malignant melanomas. The multiple mucosal and skin pigmentations are an unusual feature of this syndrome.