Identification of the Immunodominant HY
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چکیده
منابع مشابه
Identification and isolation of immunodominant proteins of Naja naja (Oxiana) snake venom
Snake venom is a complex mixture of proteins, peptides, enzymes, carbohydrates, and minerals. They contain a variety of chemicals with pharmacological and toxicological properties. The innate immune system is the first line of defense against toxins and microbes. Antibacterial and anticancer proteins produced by snake venom have recently attracted significant attention due to their relevance to...
متن کاملA continuous infusion of a minor histocompatibility antigen-immunodominant peptide induces a delay of male skin graft rejection.
We previously reported that an inhibition of antigen-specific Interferon-gamma release and cytotoxicity occurs after a continuous infusion of an HY immunodominant peptide although this treatment is not able to cause a significant delay of male skin grafts rejection. In vivo administration of high doses of an HY peptide, through mini-osmotic pumps, in naïve female mice was used to study the effe...
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Identification of hard tick species and their hosts are essential for the development of control and prevention programs for tick-borne diseases. In this descriptive cross-sectional study, ticks were collected from the sheep, goat, and camel in different regions of South Khorasan province, Iran in 2018 through cluster sampling method. Fauna and frequency of ticks were recorded and analyzed in S...
متن کاملMinimal Bystander Activation of CD8 T Cells during the Virus-induced Polyclonal T Cell Response
Acute infections with viruses such as lymphocytic choriomeningitis virus (LCMV) are associated with a massive polyclonal T cell response, but the specificities of only a small percentage of these activated T cells are known. To determine if bystander stimulation of T cells not specific to the virus plays a role in this T cell response, we examined two different systems, HY-specific T cell recep...
متن کاملHY peptides modulate transplantation responses to skin allografts.
Injection of female C57BL/6 mice with immature female bone marrow-derived dendritic cells (BMDC) pulsed with a single immunodominant HY(Db) Uty peptide, WMHHNMDLI, induces prolonged survival of syngeneic male skin grafts. In contrast, injection of immature female BMDC pulsed with a single MHC class I-restricted HY(Ab) Dby peptide, NAGFNSNRANSSRSS, causes immunization similar to that following i...
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