Persistent pruritic papules and plaques: a characteristic histopathologic presentation seen in a subset of patients with adult-onset and juvenile Still's disease.
نویسندگان
چکیده
BACKGROUND 'Persistent pruritic papules and plaques' of Still's disease represents a recently described eruption seen in a subset of patients. Most cases reported in the literature to date have been associated with adult-onset Still's disease. METHODS We present the clinical and histopathologic examinations of three female patients ranging in age from 15 to 54 years. RESULTS Our three patients each presented with clinical findings consistent with Still's disease. The youngest patient suffered from the juvenile form of Still's disease (systemic-onset juvenile rheumatoid arthritis). Each patient had a persistent, pruritic eruption with histopathologic findings of dyskeratosis confined to the upper layers of the epidermis as well as a sparse superficial dermal infiltrate containing scattered neutrophils. CONCLUSIONS These cases confirm the characteristic clinical and histopathologic findings of 'persistent papules and plaques of Still's disease' and show the potential for this eruption in both the adult and juvenile age groups.
منابع مشابه
Atypical Cutaneous Presentation Of Adult Onset Still Disease.
Adult onset still disease is a rare systemic inflammatory disease which presents with cardinal symptoms of spiking fever, arthralgia, and characteristic non pruritic evanescent salmon pink rash and neutrophilic leukocytosis. However it can have accompanied atypical cutaneous manifestations of pruritic plaques and papules. Clinicians need to be aware of this condition so that they can correctly ...
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Adult-onset Still’s disease (AOSD) is a systemic inflammatory disorder of unknown etiology that occasionally involves atypical eruptions such as persistent pruritic eruptions (PPEs) (1). We report two cases of AOSD that simultaneously showed typical eruptions and PPEs and we describe the possible histopathological findings in PPEs. Case 1 was a 53-year-old Japanese woman who was referred to our...
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ورودعنوان ژورنال:
- Journal of cutaneous pathology
دوره 37 9 شماره
صفحات -
تاریخ انتشار 2010