Pharmacoeconomics--an aid to better decision-making.

Better Reimbursement Decision-Making Based on Expected Cost-Effectiveness: Using Value of Information Decision Analysis to Improve The Design and Efficacy of A Phase Iii Program for Erlotinib.

Is there a role for pharmacoeconomics in developing countries?

The special issue of PharmacoEconomics pertaining to developing nations was a welcome move, with authors discussing various themes relating to pharmaceutical economics. The topics discussed included cost-effectiveness analyses and the future of health technology assessment (HTA) in healthcare decisionmaking in the greater Asia region. However, papers in this special issue did not provide an ans...

Multiple Criteria Decision Analysis for Health Care Decision Making--An Introduction: Report 1 of the ISPOR MCDA Emerging Good Practices Task Force.

Health care decisions are complex and involve confronting trade-offs between multiple, often conflicting, objectives. Using structured, explicit approaches to decisions involving multiple criteria can improve the quality of decision making and a set of techniques, known under the collective heading multiple criteria decision analysis (MCDA), are useful for this purpose. MCDA methods are widely ...

Tools for health care decision making: observational studies, modeling studies, and network meta-analyses.

Comparative effectiveness research incorporates study designs extending beyond the randomized controlled trial (RCT) [1], which is the touchstone for demonstrating therapeutic efficacy. The litany of RCT flaws is often recited: not real world, not real patients, not real settings, not available, not timely, and not affordable. Although not every RCT is well designed, there are established narra...

Application of an integrated decision-making approach based on FDAHP and PROMETHEE for selection of optimal coal seam for mechanization; A case study of the Tazareh coal mine complex, Iran

Increasing the production rate and minimizing the related costs, while optimizing the safety measures, are nowadays’ most important tasks in the mining industry. To these ends, mechanization of mines could be applied, which can result in significant cost reductions and higher levels of profitability for underground mines. The potential of a coal mine mechanization depends on some important fact...

Market Access and Reimbursement: The Increasing Role of Real-World Evidence.

Randomized controlled trials (RCTs) have historically been considered the primary source of evidence to support decision-making in market access and reimbursement. However, thanks to significant progress in capturing data through computerized systems and making these data available, real-world evidence (RWE) has been increasingly considered by manufacturers and payers. Despite initiatives and r...