Occult thyroid carcinoma Carcinoma tiroideo occulto

نویسنده

  • J. BOUCEK
چکیده

Some medical defi nitions remain the same for many years, others change due to the progress in the diagnostic tools, which are able to distinguish markers and symptoms until then undetectable. Occult thyroid carcinoma is a general term indicating clinically different situations, whereas the incidentally detected papillary thyroid microcarcinoma is the most important from the clinical point of view. It is fundamental, for therapeutic management, to determine biological parameters which would defi ne a small group of papillary thyroid microcarcinomas with aggressive biological behaviour. The most promising genetic and molecular markers for papillary thyroid carcinoma risk stratifi cation are discussed in this review. Preoperative evaluation of these markers, obtained through analysis of ultrasonography-guided fi ne needle biopsy specimens of papillary thyroid microcarcinoma, could be very valuable in guiding treatment of this type of cancer.

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تاریخ انتشار 2010