Drug Class Review on Skeletal Muscle Relaxants for Spasticity and Musculoskeletal Conditions
نویسنده
چکیده
The next scheduled update for this topic will be December 2003. Introduction 4 Scope and Key Questions 5 Methods 8 Literature Search 8 Study Selection 8 Data Abstraction 9 Quality Assessment 10 Data Synthesis 11 Results 11 Summary 25 References 26 Tables Table 1. Overview of included systematic reviews on skeletal muscle relaxants 38 Table 2. Overview of head-to-head trials of skeletal muscle relaxants for spasticity 40 Table 3. Overview of placebo-controlled trials of included skeletal muscle relaxants 43 Table 4. Overview of head-to-head trials of skeletal muscle relaxants for musculoskeletal conditions 46 Table 5. Overview of placebo-controlled trials of skeletal muscle relaxants for musculoskeletal conditions 48 Table 6. Adverse events, head-to-head trials of skeletal muscle relaxants for spasticity 51 Table 7. Adverse events, placebo-controlled trials of skeletal muscle relaxants for spasticity 53 Table 8. Adverse events, head-to-head trials of skeletal muscle relaxants for musculoskeletal conditions 56 Table 9. Adverse events, placebo-controlled trials of skeletal muscle relaxants for musculoskeletal conditions 58 Table 10. Summary of evidence 60 Evidence Tables Evidence Table 1. Included systematic reviews and meta-analyses of skeletal muscle relaxants in patients with spasticity 62 Evidence Table 2. Included systematic reviews and meta-analyses of skeletal muscle relaxants in patients with musculoskeletal conditions 70 Evidence Table 3. Head-to-head trials of skeletal muscle relaxants in patients with spasticity 72 Evidence Table 4. Placebo-controlled trials of skeletal muscle relaxants in patients with spasticity 99 Evidence Table 5. Head-to-head trials of skeletal muscle relaxants in patients with musculoskeletal conditions 137 Evidence Table 6. Placebo-controlled trials of skeletal muscle relaxanxt in patients with musculoskeletal conditions 149 The Agency for Healthcare Research and Quality has not yet seen or approved this report.
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