Functional Dyspepsia Postprandial distress syndrome ( PDS ) : Meal - related

Functional dyspepsia (FD) is a highly prevalent gastrointestinal disorder characterized by symptoms originating from the gastroduodenal region in the absence of underlying organic disease that readily explains the symptoms. The Rome II consensus, which defi ned FD as the presence of unexplained pain or discomfort in the epigastrium, had a number of drawbacks, including an unjustifi ed focus on pain, inclusion of a large number of nonspecifi c symptoms, and an unclear position on overlap with gastroesophageal refl ux disease (GERD) and irritable bowel syndrome (IBS). The Rome III consensus redefi ned FD as the presence of epigastric pain or burning, postprandial fullness or early satiation in the absence of underlying organic disease. Frequent overlap with GERD and IBS is acknowledged but does not exclude a diagnosis of FD. A subgroup classifi cation into postprandial distress syndrome and epigastric pain syndrome was proposed. Ongoing studies will clarify the impact of this subdivision on clinical management and treatment outcomes.