Synthesis, Crystal Structure and DNA-Binding Properties of a Cadmium(II) Complex with 2,6-Bis(N-methylbenzimidazol-2-yl)pyridine

نویسندگان

  • Huilu Wu
  • Xingcai Huang
  • Jingkun Yuan
  • Fan Kou
  • Fei Jia
  • Bin Liu
  • Ying Bai
چکیده

A new complex of Cd(II) picrate (pic) based on the ligand 2,6-bis(N-methylbenzimidazol-2-yl)pyridine (mbbp) has been synthesized and characterized by elemental analysis, electrical conductivity, 1H NMR, IR and UV/Vis spectral measurements. The crystal structure of the Cd(II) complex, [Cd(mbbp)2](pic)2, has been determined by single-crystal X-ray diffraction. The Cd(II) cation is bonded to two mbbp ligands through six nitrogen atoms, resulting in a distorted octahedral geometry. Interaction of the complex with DNA was investigated by spectrophotometric methods and viscosity measurements. The experimental results suggest that the Cd(II) complex binds to DNA in an intercalation mode.

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تاریخ انتشار 2011