Environmental and occupational respiratory diseases – 1059. Lung exposure to TiO2 induces eosinophilic airway inflammation in the rabbits
نویسندگان
چکیده
Background Titanium dioxide (TiO2) nanoparticels (NPs), one of the most abundantly utilized nanomaterials, was widely used in industry, cosmetics, and biomedicine. There have been reported that TiO2 NPs aggravates respiratory symptoms by induce pulmonary inflammation. However, the mechanisms of these effects have not been extensively studied yet. We aimed to investigate inflammation in rabbit lung following an intratracheal instillation.
منابع مشابه
Titanium Dioxide Exposure Induces Acute Eosinophilic Lung Inflammation in Rabbits
Titanium dioxide (TiO2) is increasingly widely used in industrial, commercial and home products. TiO2 aggravates respiratory symptoms by induction of pulmonary inflammation although the mechanisms have not been well investigated. We aimed to investigate lung inflammation in rabbits after intratracheal instillation of P25 TiO2. One ml of 10, 50 and 250µg of P25 TiO2 was instilled into one of the...
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