Comparative Study of Sexual Side Effects of Fluvoxamine and Fluoxetine on Patients with Major Depressive Disorder (Case Study: The Psychaitric Clinic, 22 Bahman Hospital, Mashhad)

This clinical trial aims at comparatively evaluating the side effects of two drugs of Fluvoxamine and Fluoxetine and at discussing effective factors. For this purpose, patients with unipolar major depressive disorder (MDD) are randomly placed in two groups: Fluoxetine (Abidi) with dose 10 and 40mg and Fluvoxamine (Sobhan) with dose 50 to 150-200mg. Arizona scale was filled before, one month and two months after the treatment begins, and clinical improvement of depression in the first and second months was quantitatively evaluated by Beck test. The results indicated that in treatment of patients with major depressive disorder and unipolar disorder, Fluvoxamine had less effect on their sexual desire and satisfaction from orgasm, as well as both the said drugs had positive and equal effect on improving depression.