Extranodal marginal zone B-cell lymphomas of the bilateral third eyelids in a dog
نویسندگان
چکیده
Extranodal marginal zone B-cell type lymphoma of mucosa-associated lymphoid tissue (MALT) in dogs has similar properties to human low-grade B-cell lymphoma. Both are characterised by a relatively low mitotic rate and a slow manifestation of clinical signs. Primary MALT lymphoma of the third eyelid in canines is very rare. In this case report we describe bilateral MALT lymphoma in a 21-month-old miniature poodle. Histological analysis indicated that the masses were mainly composed of lymphoid cells and lymphoepithelial lesions, a typical feature of MALT lymphoma. Immunohistochemical analysis revealed that the neoplastic cells were positive for CD79α, but negative for CD3. We believe that this case report will facilitate the diagnosis, treatment, and prognosis of canine MALT lymphoma of the third eyelid.
منابع مشابه
The management of nongastric MALT lymphomas.
The group of marginal zone B-cell lymphomas (MZL) comprises three different entities, extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (currently called MALT lymphoma), nodal marginal zone B-cell lymphoma (previously known as monocytoid lymphoma), and splenic marginal zone B-cell lymphoma (with or without circulating villous lymphocytes).[1-3] Primary splenic and no...
متن کاملPrimary CNS Marginal Zone Lymphoma: A Case Report and Review of the Literature
Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non-Hodgkin lymphoma (NHL) located in the craniospinal axis (affecting CNS, meninges and eye) without evidence of a systemic primary tumor. CNS lymphomas are typically high grade, large cell lymphomas; low grade CNS lymphomas are rare. We encountered a case of 48-year old patient with recurrent episodes of seizures,...
متن کاملChronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone B-cell lymphomas.
Chronic autoimmune or pathogen-induced immune reactions resulting in lymphoid neogenesis are associated with development of malignant lymphomas, mostly extranodal marginal zone B-cell lymphomas (MZBCLs). In this review we address (i) chemokines and adhesion molecules involved in lymphoid neogenesis; (ii) the autoimmune diseases and pathogens which are associated with development of B-cell lymph...
متن کاملLarge B-cell lymphoma in a dog: A cyto-histopathological evaluation and Immunophenotyping according to WHO classification for canine lymphomas
In the present study, we described cyto-histopathological features and immunophenotyping of the large B-cell lymphoma in an 8-year-old mixed breed dog with applying the World Health Organization (WHO) system of classification of canine lymphomas. In fine-needle aspiration (FNA), lymph nodes were involved by neoplastic cells of intermediate to large size with deep blue cytoplasm; consist of cent...
متن کاملPrimary lymphoma of the uterine horn in a Lhasa Apso dog
Primary lymphomas of the canine female genital tract are uncommon tumours. A 9-year-old intact female Lhasa Apso dog presenting with a closed pyometra underwent an ovariohysterectomy (OHE), and the hyperplastic uterine horn along with multiple follicular cysts on the right ovary was examined by histological analysis. Severe infiltration of medium-sized lymphocytes with strong positive immunorea...
متن کامل