Regular Article CLINICAL TRIALS AND OBSERVATIONS A randomized phase 3 trial of thalidomide and prednisone as maintenance therapy afterASCT in patients with MM with a quality-of-life assessment: the National Cancer Institute of Canada Clinicals Trials Group Myeloma 10 Trial
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چکیده
A. Keith Stewart,1 Suzanne Trudel,2 Nizar J. Bahlis,3 Darrell White,4 Waleed Sabry,5 Andrew Belch,6 Tony Reiman,7 Jean Roy,8 Chaim Shustik,9 Michael J. Kovacs,10 Morel Rubinger,11 Guy Cantin,12 Kevin Song,13 Kirsty A. Tompkins,14 Deb C. Marcellus,15 Martha Q. Lacy,16 Jonathan Sussman,15 Donna Reece,2 Michael Brundage,17 Erica L. Harnett,18 Lois Shepherd,18 Judy-Anne W. Chapman,18 and Ralph M. Meyer18
منابع مشابه
CLINICAL TRIALS AND OBSERVATIONS Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials
Peter M. Fayers,1,2 Antonio Palumbo,3 Cyrille Hulin,4 Anders Waage,2,5 Pierre Wijermans,6 Meral Beksaç,7 Sara Bringhen,8 Jean-Yves Mary,9 Peter Gimsing,10 Fabian Termorshuizen,11 Rauf Haznedar,12 Tommaso Caravita,13 Philippe Moreau,14 Ingemar Turesson,15 Pellegrino Musto,16 Lotfi Benboubker,17 Martijn Schaafsma,18 Pieter Sonneveld,19 and Thierry Facon,20 on behalf of the Nordic Myeloma Study Gr...
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Fred Hutchinson Cancer Research Center, Seattle, WA; Southwest Oncology Group Statistical Center, Seattle, WA; City of Hope Medical Center, Duarte, CA; University of New Mexico, Albuquerque, NM; Vancouver General Hospital, Vancouver, BC, Canada; University of Toronto, Toronto, Ontario, Canada; University of Chicago, Chicago, IL; University of Michigan, Ann Arbor, MI; Loyola University Medical C...
متن کاملCLINICAL OBSERVATIONS, INTERVENTIONS AND THERAPEUTIC TRIALS Maintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients
The role of maintenance therapy in multiple myeloma is controversial. Recent studies have shown an improvement in both progression-free and overall survival for patients receiving maintenance treatment with a combination of interferon and glucocorticoids, compared with interferon alone. The role of glucocorticoids alone as maintenance therapy has not been previously addressed. We compared alter...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Superior outcomes associated with complete response in newly diagnosed multiple myeloma patients treated with nonintensive therapy: analysis of the phase 3 VISTA study of bortezomib plus melphalan-prednisone versus melphalan-prednisone
1Centre René Gauducheau, Nantes/St Herblain, France; 2Universita di Torino, Torino, Italy; 3Dana-Farber Cancer Institute, Boston, MA; 4Praxisklinik Dr Schlag, Würzburg, Germany; 5University of Athens, School of Medicine, Athens, Greece; 6Rabin Medical Center, Petah-Tiqva, Israel; 7University of Münster, Münster, Germany; 8Belgian Myeloma Study Group, Brussels, Belgium; 9Institute of Hematology ...
متن کاملRegular Article CLINICAL TRIALS AND OBSERVATIONS Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy
Randomized, phase 2 trial of low-dose cytarabine with or without volasertib in AML patients not suitable for induction therapy Hartmut Döhner, Michael Lübbert, Walter Fiedler, Loic Fouillard, Alf Haaland, Joseph M. Brandwein, Stephane Lepretre, Oumedaly Reman, Pascal Turlure, Oliver G. Ottmann, Carsten Müller-Tidow, Alwin Krämer, Emmanuel Raffoux, Konstanze Döhner, Richard F. Schlenk, Florian V...
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