Computerized Classification of Surface Spikes in Three-Dimensional Electron-Microscopic Reconstructions of Viruses
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چکیده
Computerized classification of surface spikes in three-dimensional electron microscopic reconstructions of viruses
منابع مشابه
Averaging of Viral Envelope Glycoprotein Spikes from Electron Cryotomography Reconstructions using Jsubtomo
Enveloped viruses utilize membrane glycoproteins on their surface to mediate entry into host cells. Three-dimensional structural analysis of these glycoprotein 'spikes' is often technically challenging but important for understanding viral pathogenesis and in drug design. Here, a protocol is presented for viral spike structure determination through computational averaging of electron cryo-tomog...
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