Serum 1,25 dihydroxyvitamin D and osteocalcin concentrations in thalassaemia

نویسندگان

  • P DANDONA
  • R K MENON
  • S HOULDER
  • M THOMAS
  • A V HOFFBRAND
  • D M FLYNN
چکیده

In view of the claim that low 25-hydroxyvitamin D (25-OHD) concentrations may contribute to the pathogenesis of bone disease in patients with 13 thalassaemia major and iron overload, we have assessed the concentrations of 25-OHD, la,25 dihydroxyvitamin D (la,25(0H)2D), parathyroid hormone, and osteocalcin in such patients. 25-OHD concentrations were significantly lower in patients with thalassaemia major and iron overload than in controls and in some patients were subnormal or undectectable. la,25(OH)2D concentrations

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Serum 1,25 dihydroxyvitamin D and osteocalcin concentrations in thalassaemia major.

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تاریخ انتشار 2006