Correction: Comparing the genomes of Helicobacter pylori clinical strain UM032 and mice-adapted derivatives

نویسندگان

  • Yalda Khosravi
  • Vellaya Rehvathy
  • Wei Yee Wee
  • Susana Wang
  • Primo Baybayan
  • Siddarth Singh
  • Meredith Ashby
  • Junxian Ong
  • Arlaine Anne Amoyo
  • Shih Wee Seow
  • Siew Woh Choo
  • Tim Perkins
  • Eng Guan Chua
  • Alfred Tay
  • Barry James Marshall
  • Mun Fai Loke
  • Khean Lee Goh
  • Sven Pettersson
  • Jamuna Vadivelu
چکیده

Correction: Comparing the genomes of Helicobacter pylori clinical strain UM032 and mice-adapted derivatives Yalda Khosravi, Vellaya Rehvathy, Wei Yee Wee, Susana Wang, Primo Baybayan, Siddarth Singh, Meredith Ashby, Junxian Ong, Arlaine Anne Amoyo, Shih Wee Seow, Siew Woh Choo, Tim Perkins, Eng Guan Chua, Alfred Tay, Barry James Marshall, Mun Fai Loke, Khean Lee Goh, Sven Pettersson and Jamuna Vadivelu

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Comparing the genomes of Helicobacter pylori clinical strain UM032 and Mice-adapted derivatives

BACKGROUND Helicobacter pylori is a Gram-negative bacterium that persistently infects the human stomach inducing chronic inflammation. The exact mechanisms of pathogenesis are still not completely understood. Although not a natural host for H. pylori, mouse infection models play an important role in establishing the immunology and pathogenicity of H. pylori. In this study, for the first time, t...

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Helicobacter pylori is a highly successful gastric pathogen. High genomic plasticity allows its adaptation to changing host environments. Complete genomes of H. pylori clinical isolate UM032 and its mice-adapted serial derivatives 298 and 299, generated using both PacBio RS and Illumina MiSeq sequencing technologies, were compared to identify novel elements responsible for host-adaptation. The ...

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عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2014