Amniocytes Cytogenetical Study of 100 High Risk Pregnant Women with Chromosomal Abnormalities by Using Gtg Banding High Resolution Method

Early detection of abnormalities in early pregnancy and they can be terminated once the baby was born with a disability that economic, social and cultural rights, there are a lot of families and community and overhead families and community prevent, so far none of the known human chromosomal abnormalities are treatable and the only way to deal with these diseases limit to prenatal diagnosis and abortion of affected. The purpose of this study is examine amniocytes cytogenetic of pregnant women with high-risk study of chromosomal anomalies to determine the number of disorders and structural chromosome in the study population to identify and information to families and early pregnancies as a result of such termination and the effects of these abnormalities and prevent families from the burden of economic, social and cultural kept safe. In this functional practical study fetal chromosomal abnormalities in 100 high risk of chromosomal anomaly screening and identification of numerical and structural chromosome abnormalities were studied. Amniotic fluid was cultured for this purpose to prepare karyotype and high resolution Gtg method Bndyng metaphase cells were studied. Results of amniotic fluid culture and chromosome typing and GTG bonding High resolution trisomy 21 most frequent in the trisomy (2 percent) and seven per cent of all fetal abnormalities construction have been as follows four percent of those with inv 9, one percent of Atypic y additional band on chromosome 15 and two percent, respectively. The results suggest that detection of fetal chromosomal anomalies mothers with high risk cytogenetic testing amniotic fluid can be effective in detecting chromosomal abnormalities as well as the results show the effectiveness of this method for prenatal diagnosis timely notification to the families of the birth of chromosomally abnormal embryos prevented.