Synthesis of clickable amphiphilic polysaccharides as nanoscopic assemblies.

نویسندگان

  • Liye Fu
  • Lingyao Li
  • Jun Wang
  • Kyle Knickelbein
  • Lin Zhang
  • Ian Milligan
  • Yi Xu
  • Kylie O'Hara
  • Lindsay Bitterman
  • Wenjun Du
چکیده

The synthesis of clickable polysaccharides was achieved by using alkynylated 1,6-anhydro glucopyranose as a monomer and BF3·OEt2 as an effective catalyst. Subsequent click conjugation with polyethylene glycol (PEG) afforded PEG-grafted polysaccharides in nearly quantitative efficiency.

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عنوان ژورنال:
  • Chemical communications

دوره 50 84  شماره 

صفحات  -

تاریخ انتشار 2014