Mobilization of qnrB2 and ISCR1 in plasmids.

نویسندگان

  • Ying-Tsong Chen
  • Tsai-Lien Liao
  • Yen-Ming Liu
  • Tsai-Ling Lauderdale
  • Jing-Jou Yan
  • Shih-Feng Tsai
چکیده

The DNA sequences of two IncHI2 plasmids, pEC-IMP and pEC-IMPQ, from metallo-beta-lactamase-producing Enterobacter cloacae clinical isolates were determined. The two conjugative plasmids are almost identical, but pEC-IMPQ carries an additional segment containing an orf513 (ISCR1), a truncated 3' conserved sequence, and a qnrB2. Comparative analyses provide support for the proposed ISCR1-mediated gene mobilization.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 53 3  شماره 

صفحات  -

تاریخ انتشار 2009