Fever in a Hyper-Endemic Malarial Area
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Hyper-reactive Malarial Splenomegaly (HMS) in a patient with β thalassaemia syndrome
This report describes a case of hyper-reactive malarial splenomegaly in a patient with a thalassaemia syndrome. Increased haemoglobin A2 is valuable for the diagnosis of common forms of β-thalassemia, while haemoglobin F (HbF) helps in diagnosis of the rarer δβ- forms. Thalassemia is characterised by splenomegaly and is common in malaria endemic areas. Hyper-reactive malarial splenomegaly is al...
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was but a manifestation of the same protean affection. The Malarial Commission of the Royal Society first threw doubt on this simple view by showing that malarial parasites were nearly always absent from cases of chronic fever with very large spleens in Calcutta, and that tiie " endemic index of malaria," or the percenlage of healthy children showing malarial parasites in their blood, was nil i...
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Background: Crimean-congo hemorrhagic fever (CCHF) is an acute tick-borne viral, zoonotic disease with hemorrhagic manifestations and considerable mortality in humans. The purpose of this study was to introduce CCHF as a case report from Babol, north of Iran. It is known as an endemic pathogen in some regions of Iran.Case presentation: We present a case of CCHF suffering from sudden onset of fe...
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Malaria infections in pregnancy are associated with adverse outcomes for both mother and child. There are few data on hyper-reactive malarial splenomegaly, an aberrant immunological response to chronic or recurrent malaria in pregnancy. This retrospective assessment reviewed the impact of mefloquine treatment on pregnant women with suspected hyper-reactive malarial splenomegaly in an area of lo...
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