4D in-beam PET of moving targets for different irradiation scenarios
نویسندگان
چکیده
Introduction Ion therapy allows a high precision, tumor conformal dose application but it is very sensitive to density changes along the beam path. Intra-fractional tumor motion due to respiration increases the risk of an incorrect irradiation and thus requires a reliable dosimetry as it was done by means of 3D in-beam PET for more than 400 patients at the experimental heavy ion treatment facility at GSI Darmstadt. A new beam delivery system for tracking moving targets with the scanned ion beam has been developed at GSI [1] and first experiments have shown the feasibility to correct the in-beam PET measurements for target motion [2]. Now the potential of this new 4D in-beam PET method for detecting possible malfunctions of the motion compensated dose application is under investigation.
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