CALL FOR PAPERS Innovative and Emerging Technologies in GI Physiology and Disease Colonic inflammation and secondary bile acids in alcoholic cirrhosis
نویسندگان
چکیده
Genta Kakiyama, Phillip B. Hylemon, Huiping Zhou, William M. Pandak, Douglas M. Heuman, Dae Joong Kang, Hajime Takei, Hiroshi Nittono, Jason M. Ridlon, Michael Fuchs, Emily C. Gurley, Yun Wang, Runping Liu, Arun J. Sanyal, Patrick M. Gillevet, and Jasmohan S. Bajaj Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University and McGuire Veterans Affairs Medical Center, Richmond, Virginia; Department of Microbiology, Virginia Commonwealth University and McGuire Veterans Affairs Medical Center, Richmond, Virginia; Department of Immunology, Virginia Commonwealth University and McGuire Veterans Affairs Medical Center, Richmond, Virginia; Junshin Clinic Bile Acid Institute, Tokyo, Japan; and Microbiome Analysis Center, George Mason University, Manassas, Virginia
منابع مشابه
CALL FOR PAPERS Innovative and Emerging Technologies in GI Physiology and Disease Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation
Jasmohan S. Bajaj, Phillip B. Hylemon, Jason M. Ridlon, Douglas M. Heuman, Kalyani Daita, Melanie B. White, Pamela Monteith, Nicole A. Noble, Masoumeh Sikaroodi, and Patrick M. Gillevet Division of Gastroenterology, Hepatology and Nutrition; Department of Microbiology, Virginia Commonwealth University and McGuire Veterans Affairs Medical Center, Richmond, Virginia; and Microbiome Analysis Cente...
متن کاملColonic inflammation and secondary bile acids in alcoholic cirrhosis.
Alcohol abuse with/without cirrhosis is associated with an impaired gut barrier and inflammation. Gut microbiota can transform primary bile acids (BA) to secondary BAs, which can adversely impact the gut barrier. The purpose of this study was to define the effect of active alcohol intake on fecal BA levels and ileal and colonic inflammation in cirrhosis. Five age-matched groups {two noncirrhoti...
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Alcoholic liver disease (ALD) is one of the major causes of liver morbidity and mortality worldwide. Chronic alcohol consumption leads to development of liver pathogenesis encompassing steatosis, inflammation, fibrosis, cirrhosis, and in extreme cases, hepatocellular carcinoma. Moreover, ALD may also associate with cholestasis. Emerging evidence now suggests that farnesoid X receptor (FXR) and ...
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