Overexpression of estrogen receptor α increases hepatic cholesterogenesis leading to biliary hypersecretion in mice
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منابع مشابه
Overexpression of estrogen receptor alpha increases hepatic cholesterogenesis, leading to biliary hypersecretion in mice.
We explored whether there is an "estrogen-ERalpha-SREBP-2" (for estrogen-estrogen receptor subtype alpha-sterol-regulatory element binding protein-2) pathway for regulating hepatic cholesterol biosynthesis in ovariectomized AKR mice treated with 17beta-estradial (E2) at 6 microg/day or E2 plus the antiestrogenic agent ICI 182,780 at 125 microg/day and on chow or fed a high-cholesterol (1%) diet...
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We explored whether there is an ‘‘estrogen-ERaSREBP-2’’ (for estrogen-estrogen receptor subtype a-sterolregulatory element binding protein-2) pathway for regulating hepatic cholesterol biosynthesis in ovariectomized AKR mice treated with 17b-estradial (E2) at 6 mg/day or E2 plus the antiestrogenic agent ICI 182,780 at 125 mg/day and on chow or fed a high-cholesterol (1%) diet for 14 days. To mo...
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