Recent advances in coeliac disease.

Recent advances in clinical practice RECENT ADVANCES IN COELIAC DISEASE

Correspondence to: Professor D A van Heel, Institute of Cell and Molecular Science, Barts and The London, Queen Mary’s School of Medicine and Dentistry, Turner St, London E1 2AD, UK; [email protected] _________________________ T he management of coeliac disease is an increasing part of a gastroenterologist’s workload. Recent prevalence studies suggest ,1% of the general UK population have po...

Advances in coeliac disease.

PURPOSE OF REVIEW The number of people diagnosed with coeliac disease continues to rise, and this article critically summarizes recent research into the condition. RECENT FINDINGS Much work has been focused on clarifying the molecular pathways involving cytokines in coeliac disease. Such work will yield improved understanding of the complex pathogenesis of coeliac disease and novel therapeuti...

Recent advances in coeliac disease.

Symposium on 'The challenge of translating nutrition research into public health nutrition'. Session 3: Joint Nutrition Society and Irish Nutrition and Dietetic Institute Symposium on 'Nutrition and autoimmune disease'. Recent advances in genetic understanding of coeliac disease.

Over the past 20 years major advances have been made in the diagnosis and understanding of pathogenic mechanisms relating to coeliac disease. Recently-identified genetic markers support the immunological-inflammatory nature of the disease. It is hoped that these newly-identified genes will assist further dissection of the inflammatory pathways in coeliac disease and give insight into why certai...

Review article: coeliac disease, new approaches to therapy.

BACKGROUND Coeliac disease is managed by life-long gluten withdrawal from the diet. However, strict adherence to a gluten-free diet is difficult and is not always effective. Novel therapeutic approaches are needed to supplement or even replace the dietary treatment. AIM To review recent advances in new therapeutic options for coeliac disease. METHODS A literature search was performed on MED...

A young girl with H syndrome and coeliac disease

H syndrome is an autosomal recessive genodermatosis with reports dating back to the last decade. This syndrome is caused by mutations in the SCL29A3 gene. The clinical characteristics of this syndrome consist of dermatological manifestations, including hyperpigmented, hypertrichotic, and indurated patches and plaques. It affects various systems by causing heart anomalies, hepatosplenomegaly, hy...