Optimal experimental design for event-related fMRI.

Analysis of fMRI Timeseries: Linear Time-Invariant Models, Event-related fMRI and Optimal Experimental Design

Event-related fMRI contrast when using constant interstimulus interval: theory and experiment.

Event-related functional magnetic resonance imaging (ER-fMRI) involves the mapping of averaged hemodynamic changes resulting from repeated, brief (<3 sec) brain activation episodes. In this paper, two issues regarding constant-interstimulus interval ER-fMRI were addressed. First, the optimal interstimulus interval (ISI), given a stimulus duration (SD), was determined. Second, the statistical po...

Multi-objective optimal experimental designs for event-related fMRI studies

In this article, we propose an efficient approach to find optimal experimental designs for event-related functional magnetic resonance imaging (ER-fMRI). We consider multiple objectives, including estimating the hemodynamic response function (HRF), detecting activation, circumventing psychological confounds and fulfilling customized requirements. Taking into account these goals, we formulate a ...

Event-related fMRI in cognition

A primary advantage of functional magnetic resonance imaging (fMRI) over other techniques in neuroscience is its flexibility. Researchers have used fMRI to study a remarkable diversity of topics, from basic processes of perception and memory, to the complex mechanisms of economic decision making and moral cognition. The chief contributor to this experimental flexibility-indeed, to the growth of...

A Fast Algorithm for Constructing Efficient Event-Related

7 We propose a novel, efficient approach for obtaining high-quality experimental designs for 8 event-related functional magnetic resonance imaging (ER-fMRI). Our approach combines a 9 greedy hillclimbing algorithm and a cyclic permutation method. When searching for optimal 10 ER-fMRI designs, the proposed approach focuses only on a promising restricted class of 11 designs with equal frequency o...