Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.
نویسندگان
چکیده
New multivalent RGD-containing macromolecules were designed by exploiting two orthogonal chemoselective ligations. They were next applied to a competitive cell adhesion assay and used for the non invasive optical imaging of tumour in small animals.
منابع مشابه
Click chemistry for the synthesis of RGD-containing integrin ligands.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 8 22 شماره
صفحات -
تاریخ انتشار 2010