Dynamics and Scaling of Single DNA Molecules in Forces and Flows
نویسنده
چکیده
We numerically examine the extension of tethered worm-like chains in shear flow, obtaining agreement with scaling arguments that invoke thermal fluctuations and the specific nonlinearity of the WLC force law. The transient tension distribution is obtained and likewise found to reflect nonlinearity and finite extensibility. Cyclic dynamics of the chain free end are observed. Numerical simulations are also performed for electric field-driven WLCs colliding with mobile obstacles. Unhooking time is shown to agree with a theoretical model derived for stationary obstacles.
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تاریخ انتشار 2008